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The name of an interesting show with Dr. Michael Mosley on the ancient idea and science of fasting to improve health and extend life. In it, he discussed Insulin-like Growth Hormone (IGF-1), and its role in accelerating aging and aging of the brain, and increasing risks of developing seven types of cancer.
They studied a group in Ecuador with a disorder known as Laron syndrome. This population has very low levels of IGF-1 paired with extremely low levels of diabetes and cancer, despite living unhealthy lifestyles.
By fasting for 3.5 days eating one 50 calorie soup per day and water for fluids, he decreased his IGF-1 by 50%.
Studies with mice have produced significant results. Studies on humans are currently underway at UIC.
Knowing that a 4 day fast in regular life would be difficult, he was recommended by a Dr to a 5/2 diet. 5 days regular eating/caloric intake, 2 days with a 600 calorie total. After 5 weeks, his IGF-1 decreased 50%. His high risk status(cardiometabolic workup) prior to dieting for developing CVD, CVA, MI, CHF, and diabetes was reduced to "1 in a million" per the doc. Body fat decreased from 27% to 19%. Fasting glucose, LDH, total cholesterol, triglycerides, and BP all decreased. HDL went up.
Not sure when this documentary was made? Has anyone tried this method?